Journal of Computer Aided Surgery Vol.5 No.3-2


手術情報の4次元ログ記録標準フォーマット

○櫻木 太a,b, 中島義和b,a,佐藤嘉伸b,a,米延策雄e, 菅野伸彦c, 橋爪誠f, 吉川秀樹c, 越智隆弘g,d, 田村進一b,a
a.大阪大学大学院情報科学研究科コンピュータサイエンス専攻
大阪大学大学院医学系研究科 b. 多元画像解析分野,c. 器官制御外科学講座, d.ロボティクス治療学分野
e.国立大阪南病院
f.九州大学大学院医学研究院災害救急医学
g.国立相模原病院

Standard format for recording 4-D surgical information

F.Sakuragi a,b, Y.Nakajima b,a, Y.Sato b,a, K.Yonenobu e,N.Sugano c, M.Hashizume f, H.Yoshikawa c, T.Ochi g,d, S.Tamura b,a
a.Dept. of Computer Science , Osaka University Graduate School of Information Science and Technology
b.Div.of Interdisciplinary Image Analysis
c.Dept. of Orthopaedic Surgery
d.Div. of Robotic Therapy ,Osaka University Graduate School of Medicine
e.Osaka Minami National Hospital
f.Dept.of Disaster and Emergency medicine, Graduate School of Medical Sciences, Kyushu University
g.National Sagamihara Hospital

Abstract: Recording surgical information is important , because it is useful for various purpose, such as quantitiative validation of surgery and cleaning up the causes of unexpected occurrence in an operation. However, quantity and variety of recorded data become larger, it is more difficult to manage and analyze it totally. we have been developing a total computer management system of surgical information and a framework of surgery reporting. In this paper, we propose a standard format for recording surgical information and apply to various surgical navigation systems for ensuring its effectiveness.
Keywords: integration of surgical information, surgical navigation system, surgery report, XML


高信頼性・高安全性外科手術支援ロボットシステムの設計

○織田村元樹(東大),岡田昌史(東大),中村仁彦(東大)

High Reliability and Security of Surgical Robot System

*Motoki Odamura (Univ. of Tokyo), Masafumi Okada (Univ.of Tokyo), Yoshihiko Nakamura (Univ. of Tokyo)

Abstract: Breakdown of surgical robot systems can cause fatal trouble because human work in the working area of these robot deffer from industrial robots. So these system require high security and reliability. In this paper, we propose the thchniques which realize the high security and reliability of the surgical robot system, and enhance security and reliability of the surgical robot system.
Keywords: Surgical Robot, Security, Reliability


認知モデルによる手術操作解析の試み

○篠原一彦,苗村潔
東京工科大学バイオニクス学部

A basic analysis of surgical procedure by the cognitive model

Kazuhiko Shinohara, Kiyoshi Naemura
School of Bionics, Tokyo University of Technology

Abstract: A cognitive analysis of the procedure of laparoscopic cholecystectomy by the Rasmussen's model was performed in this study. Elemental operations such as dissection, hemostasis and suturing were classified into " skill based " behavior, and strategies for complication and unexpected events were classified into "rule based " and "knowledge-based" behaviors. Process analysis by Rasmussen's model is useful for work-analysis of the surgical procedure in the resurch and development of surgical manipulators and simulators.
Keywords: Rasmussen's cognitive model , process analysis, surgical procedure


立体内視鏡による手術操作の評価指標に関する検討

○山内康司1, 篠原一彦2
1.産業技術総合研究所治療支援技術グループ
2.東京工科大学バイオニクス学部

Metrics for surgical task performance in three-dimensional endoscope

Yasushi Yamauchi 1, Kazuhiko Shinohara 2
1.Surgical Assist Technology Group , National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan
2.School of Bionics, Tokyo University of Technology, Tokyo , Japan

Abstract: (Objective) A three-dimensional (3D) endoscope can provide stereopsis , an important depth cue, but gazing at the stereoscopic display long time is reported to give surgeons excessive visual fatigue. We studied its effect on the laparoscopic manipulation, and evaluated it in both objective and sensory scores. (Methods) A 3D laparoscope is used to provide both 2D and 3D visions, by switching video signals. 24 non-medical subjects performed endoscopic tasks in 2D and 3D vision. In both visual conditions, subjects repeatedly reach targets ( one randomly selected among ten) with the tip of forceps for five minutes. Objective scores are evaluated by the average time of each task. Sensory analysis includes questions about fatigue, depth perception and stereopsis. (Results) We found significant improvement of performance in subjects who performed tasks in 3D after 2D (p <0.01). No improvement was observed in subjects who performed tasks in 2D after 3D (p > 0.10). Nine subjects could not correctly distinguish between 2D and 3D. (Conclusion) Although learning effect is dominant, 3D vision improved laparoscopic performance. Sensory analysis needs further examination with longer and complex tasks.
Keywords: depth perception, laparoscopy


内視鏡用非接触硬さイメージャ

○川原知洋*,田中信治**,金子 真*
*広島大学工学研究科
**広島大学医歯薬学総合研究科

Non-contact Stifness Imager for Endoscope

○T.Kawahara*, S.Tanaka**, M.Kaneko*
*Graduate School of Engineering, Hiroshima University , Hiroshima, Japan
**Graduate School of Science , Hiroshima University, Hiroshima, Japan

Abstract: We propose the " Non-contact Stiffiness Imager for Endoscope" that can detect the relative stiffiness as a visual pattern. The sensor is conposed of an air-supply nozzle for imparting a force to the environment and a CCD camera for detecting a pattern. The CCD camera obtains a contour map pttern using the bringhtness distribution of the light source of endoscope. In order to emphasize the change of brightness due to the displacement of environment, we utilize the light saturation method where we focus on the lower bit image for the obtained data multiplied by an appropriate factor α.Basic experimental results using an endoscope are also shown.
Keywords: Endoscope, Non-contact, Air Flow, Stiffiness Imager, Contour Map Pattern


ウエッジプリズムを用いた視野可変腹腔鏡の開発(第4報)〜視野移動評価実験〜

○橋本健正1, 小林英津子1, 佐久間一郎1, 小西晃造2, 橋爪誠2, 土肥健純3,
1.東京大学大学院新領域創成科学研究科
2.九州大学大学院災害・救助医学
3.東京大学大学院情報理工学系研究科

Development of laparoscope using wedge prisms that has flexible viewpoint (The 4th Paper) 〜Evaluation of viewpoint movement 〜

Takemasa Hashimoto 1, Etsuko Kobayashi 1, Ichiro Sakuma 1, Kozo Konishi 2, Makoto Hashizume 2, Takeyoshi Dohi 3
1.Graduate School of Frontier Sciences, The University of Tokyo
2.Department of Disaster and Emergency Medicine, Graduate School of Medical Sciences, Kyushu University
3.Graduate School of Information Science and Technology, Tne University of Tokyo

Abstract: This paper introduces a laparoscope using wedge prisms that has flexible viewpoint . Principle of this devise was reported in the 1st paper. Ways to make size smaller and reduce eclipse were reported in the 2nd paper. And estimation of image quality and how to make it move were reported in the 3rd paper. In this paper, we report a new algorism to actuate the laparoscope and evaluation of this algorism. Using the new algorism, the laparoscope's viewpoint can move faster and more accurately than ever one. When it moves to direction of 45 degree , average of positioning error is 1.2mm . Finally, we report results of Pig experiments, the laparoscopic image was good without noise, and it moved smoothly in the abdominal cavity.
Keywords: Laparoscope, Wedge Prism, Minimally invasive Surgery, Medical Robot


二視野同時観察が可能な内視鏡の開発 第2報 操作性向上

○伊藤栄一a, 関谷尊臣a, 松本光弘a, 金井守康a, 山内康司b, 山下樹里b, 森川治b, 橋本亮一b, 福井幸男c, 横山和則d, 福与恒雄e, 橋本大定f, 伊関洋g, 高倉公朋g
a.ペンタックス株式会社R&Dセンター
b.産業技術総合研究所
c.筑波大学
d.耳鼻咽喉科@つくば南大通り
e.新興光器製作所
f.埼玉医大
g.東京女子医大

Development of a dual-view endoscopic system vol.2

E.. Ito a, T. Sekiya a, M . Matsumoto a, M. Kanak a, Y. Yamauchi b, J. Yamashita b, O. Morikawa b, R. Hashimoto b, Y. fukui c, K.Yokoyama d, T. Fukuyo e, D.Hashimoto f, H.Iseki g, K. Takakura g
a.Research & Development Center , PENTAX Corporation
b.National Institute of Advanced Industrial Science and Technology (AIST)
c.Institute of Information Sciences and Electronics, University of Tsukuba
d.ENT Clinic @ Tsukuba South Avenue
e.Shinko Optical
f.Saitama Medical Canter, Saitama Medical School
g.Dept. of Neurosurgery , Tokyo Women's Medical University

Abstract: We developed an endoscope system that provides two different views simultaneously, one is a wide view (120 degrees) and the other is an enlarged view with image-shifting mechanism. As an additional this paper the accuracy of the mechanism and a control feeling for the switch are described.
Keywords: endoscope, image shift, dual-view


内視鏡把持装置Naviot TM 58臨床適用例の検討

○安永武史a,b, 橋爪誠a, 奥山稔朗f, 起田桂志f, 小林英津子d, 小西晃造a, 土肥健純c, 佐久間一郎d, 島田光生e, 前原喜彦e, 宮本 潮b
a.九州大学大学院災害・救急医学
b.日立製作所医療事業推進センター
c.東京大学大学院情報理工学系研究科
d.東京大学大学院新領域創成科学研究科
e.九州大学大学院消火器・総合外科(第二外科)
f.貝塚病院

Remote-controlled endoscope positioning system, Naviot, for endoscopic surgery

T. Yasunaga a,b, M.Hashizume a, T. Okuyama f, K. Okita f, E.. Kobayashi d, K. konishi a, Y. Dohi c, I. Sakuma d, M.Shimada e, Y. Maehara e, S.Miyamoto b
a.Department of Disaster and Emergency Medicine,and e.Department of Surgery and Science, Graduate School of Medical Sciences , Kyushu University,
c.Graduate school of Information Science and Technology, and d. Frontier Sciences, The Univ. of Tokyo
b.Medical System Div. Hitachi Ltd.
f.Kaizuka Hospital

Abstract: A remote-contorolled endoscope positioning system, NaviotTM (Hitachi Ltd.), was newly developed and applied to an endoscopic surgery on 58 patients; laparoscopic cholecystectomy,splenectomy, inguinal herniorrhaphy, appendectomy, colectomy, Nissen fundplication , prostatectomy, sympathectomy, extirpation of mediastinal tumor, lobectomy, oophorectomy, hysterectomy. A surgeon could easily control the zoom and the 8 directions of the laparoscopic movement. NaviotTM replaced the surgeon who holds the camera , and enabled surgeons to perform " solo surgery " on laparoscopic inguinal herniorrhaphy and appendectomy.
Keywords: Remote-contorolled endoscope positioning system, Laparoscopic inguinal herniorrhaphy, Solo surgery


コンベックス型三次元超音波内視鏡による構築画像の精度および再現性の評価

○炭山和毅*,鈴木直樹**,角谷 宏*,田尻久雄*
*東京慈恵会医科大学内視鏡科
**東京慈恵会医科大学高次元医用画像工学研究所

Geometrical Accuracy and Reproducibility of Convex Type Three-Dimensional Endoscopic Ultrasound

Kazuki Sumiyama*, Naoki Suzuki**, Hiroshi Kakutani*, HIsao Tajiri*
* The Department of Endoscopy, Jikei Univ. Sch. of Med
**Institute for High Dimensional Medical Imaging., Jikei Univ. Sch. of Med.

Abstract: Convex type endoscopic ultrasound(EUS) has been recognized as an essential device for hemodynamic analysis using its Doppler mode and guide for various interventional diagnostic and therapeutic procedures using needle puncture technique . The major disadvantage of convex type EUS is the sector-shaped smaller longitudinal acoustic window. Examiner must convey scanning only with guidance of this small acoustic window without endoscopic view. Consequently, reproducibility of the convex type EUS is not so high as other types of EUS. To overcome these difficulties , we developed a three-dimensional convex type EUS (3D-CEUS) and previously reported its clinical feasibility. In this study, we quantitatively evaluated accuracy and reproducibility of 3D-CEUS in a phantom study. We will discuss the accuracy and reproducibility of the system using results of the phantom study and several clinical images.
Keywords: Endoscopic ultrasongraphy, animal study, three-dimensional image.


デザイン手法による全置換型人工腎臓基本形態へのアプローチ

○小倉琢也,川崎和男
名古屋市立大学大学院芸術工学研究科

An Approach to a Basic Model of Total Artificial Kidney using Design Method

Takuya Kokura, Kazuo Kawasaki
Graduate School of Design and Architecture, NAGOYA CITY UNIVERSITY

Abstract: Although Total Artificial Kidney(TAK) need to be realized for the renal patient, the present condition is that even the basic form does not exist. Various problems, such as material science , living body dynamism, an osmosis film, and the casting method, are mentioned to this problem. This study aims at designing the basic form of TAK using the design technique from a viewpoint of a design. The basic form was approached from both directions of a macroscopic viewpoint and a microscopic viewpoint, and the morphlogy which introduced topology considered the substantiation.Consequently, the concept of TAK was made into the distributed processing type artificial kidney from the macroscopic viewpoint, and the form on the topology of dogbone space was chosen as the form image. Morever, the automatically generable form was used by the program to the pipe in the kidney which changes while branching with micrometer from a millimeter. From the microscopic viewpoint , the design image was given to the part which performs the important function of the kidney; filtration and re-absorption.
Keywords: Total Artificial Kidney, Morphology , Topology, Dogbone Space, Macroscopic and Microscopic Approach


埋め込み型下顎骨延長器およびその遠隔操作システムの開発

藤本英雄a, 佐野明人a, ○坂口正道a, 森田祐介a, 澤木佳弘b, 上田実b
a.名古屋工業大学大学院工学研究科
b.名古屋大学大学院医学系研究科

Development of Mandibular Osteogenic Distractor and Its Teleoperation System

H.Fujimoto a, A. Sano a, M. Sakaguchi a, Y. Morita a , Y. Sawaki b, M. Ueda b
a.Graduate School of Engineering , Nagoya Institute of Technology, Nagoya, JAPAN
b.Graduate School of Medicine, Nagoya University, Nagoya, JAPAN

Abstract: In recent years, the callus extending method is capturing the spotlight as a care to aplasia and the deficit of a jawbone. We develop the embedding type automatic extension machine equipped with many merits compared with the conventional manual extension machine. Moreover,we examine the system in which monitoring of somewhere is possible by using a network.
Keywords: distraction osteogenesis, mandibular lengthening, teleoperation, mechatronics, network


細胞手術のための光駆動マイクロマシンの研究
Study on Optically driven micromachine for cell surgery

丸尾昭二,生田幸士,小川雅史,○伊藤季延(名古屋大学)
Shoji Maruo, Koji Ikuta, Masafumi Ogawa, Suenobu Itoh (Nagoya University)

Abstract: Optically driven micromachine were made by use of two-photon microstereolithography with 140 nm resolution. The nanoneedle is attached to a dot named " Optical trap point" to control the movement just by a single laser beam . Since the driving performance of the nanoneedle depends on laser power and the shape and size of the optical trap point , we have developed the laser manupulation system using hight power YAG laser and optimized the diameter and the height of column-like optical trap point. By the laser manupulation system and the optimization of the optical trap point , the nenoneedle offers the torque on the order of fN to pN. The driving frequency of translational motion was also attained to 12 Hz. Such optically driven nanotools will be widely applied to micro/nano biotechnology.
Keywords: Optically driven micromachine, Two-photon Absorption, Microstereolithography, Laser Trapping


生分解樹脂用3次元微細加工法の研究(第1報)高分解能・高速造形装置の開発

生田幸士,○山田 章,新倉史智(名古屋大学工)

Three-dimensional Microfabrication for Biodegradable Polymers (1st report) Toward High-resolution and High-speed process

Koji Ikuta, * Akira Yamada, Fuminori NIikura (Nagoya University, School of Engineering)

Abstract: We have developed a novel three-dimensional micro fabrication process with high-resolution and high-speed for biodegradable polymers. The designed system allows us to process micro-level forms by extruding and scanning heated and melted polymers from the nozzle. We adopted a batch process to supply materials in order to eliminate the prior process that employs toxic solvents. In addition , we are able to handle almost all the biodegradable thermoplastic resins by adopting this system . To realize high-accuracy, we design very small-opening nozzle with highly customized fabrication parameters. This renders it possible to process with the resolution of 50 μm. Poly (lactide)(PLA) enables us to process millimeter-sized structures such as micro pipes, bending pips, and coil springs in less than 10 minutes. The shape of the structures can be easily changed and quickly modified . Our system is expected to have potential applications in optimum design and fabrication of implantable devices.
Keywords: Biodegradable , Three-dimentional , Microfabricationk High-resolution


骨折整復支援ロボティックシステムにおける画像ナビゲーション

○中島義和a,d, 古結義浩e, 田代孝仁a,d,岡田俊之a,d,佐藤嘉伸a,d,鮫島誠e, 菅野伸彦b, 斉藤正伸f, 米延策雄f, 光石衛g, 佐久間一郎h, 吉川秀樹b, 越智隆弘i,c,田村進一a,d
大阪大学大学院{医学形研究科a{多元的画像解析分野,b 器官制御外科学,c ロボティックス治療学},d 情報科学研究科}
e.三菱重工業株式会社
f.国立大阪病院
東京大学大学院{g 工学系研究科,h 新領域創成科学研究科}
i.国立相模原病院

Image-based Navigation in a Robotic System for Bone Fracture Reduction

Y.Nakajima a, d, Y. Koketsu e, T.Tashiro a,d, T.Okada a,d, Y. Sato a,d, M.Samejima e, N.Sugano b, M.Saito f, K.Yonenobu f, M.Mitsuishi g, I.Sakuma h, H.Yoshikawa b, T.Ochi i,c, S.Tamura a,d
{{a Div.of Interdisciplinary Image Analysis, b Dept. of Orthopaedic Surgery,c Div. of Robotic Theraoy}, Graduate School of Medicine
d.Graduate School of Information Science and Technology}, Osaka University
e.Mitsubishi Heavy Industries, Ltd.,
f.Osaka Minami National Hospital
{g. Graduate School of Engineering, h. Graduate School of Frontier Sciences}, the University of Tokyo
i.National Sagamihara Hospital

Abstract: We have developed a robotic system for the reduction of bone fracture. In this paper, we describe an image-based navigation system as a component of the robotic system. Voxel-based 2-D/3-D registration and volume registration techniques are employed for the detection of bone fragment positions and the determination of reposition path, respectively. All coordinate systems are integrated in the navigation and then robot is controlled . The results of accuracy validation by using computer simulation are shown.
Keywords: computer aided surgery, bone fracture reduction, 2-D/3-D registration, volume registration


反対側を利用した大腿骨骨折整復計画とその精度検証

○岡田俊之a,d,渡邊曜子a,d,中島義和a,b, 佐藤嘉伸a,b, 小山毅c, 菅野伸彦c, 米延策雄e, 吉川秀樹c, 越智隆弘d,f,田村進一a,b
a.大阪大学大学院情報科学研究科コンピュータサイエンス専攻
b.大阪大学大学院医学形研究科多元的画像解析分野,c.器官制御外科学講座,d.ロボティックス治療学分野}
e.国立大阪南病院
f.国立相模原病院

Preoperative planning of Femur Fracture Reduction Using Contralateral Bone Image and Its Accuracy Validation

Toshiyuki Okada a,d, Yoko Watanabe a,b, Yoshikazu Nakajima a,b, Yoshinobu Sato a,b, Tsuyoshi Koyama c, Nobuhiko Sugano c, Kazuo Yonenobu e, Hideki Yoshikawa c, Takahiro Ochi d,f, Shinichi Tamura a,b
a.Dept. of Computer Science, Osaka University Graduate School of Information Science and Technology
{b.Div. of Interdisciplinary Image Analysis, c.Dept. of Orthopaedic Surgery, d.Div. of Robotic Therapy} Osaka University Graduate School of Medicine
e.Osaka Minami National Hospital
f.National Sagamihara Hospital

Abstract: The number of cases of femur fracture is increasing with progress of an aging society year by year. The research of the robotic system and navigation system is widely done in orthopedics. In these computer aided systems,it is the one of the important subjects how to reduce fracture accurately. In this study, we focused attention on the body symmetry, applied fracture reduction planning using contralateral bone, and validated its accuracy. In fracture reduction planning, we register between the mirror image of the contralateral bone and the proximal or distal fragments using the preoperative CT image, and calculate the relative positions the healty bone. Using relative position and orientation of the healthy bone as the ground truth, accurate validation is available. In the experiments, bias of translation and rotation were 4.0 mm and 2.3 degrees and precision of those were 0.23mm and 0.71degrees.
Keywords: fracture reduction,preoperative planning, contralateral bone, volume registration


複数X線像とCT間のレジストレーションを用いた前十字靭帯再建術のためのナビゲーションシステム

○1空閑 護,2 安田和則,1波多伸彦,1土肥健純
1.東京大学大学院情報理工学研究科
2.北海道大学大学院医学研究科外科治療学

A Navigation System for ACL Reconstruction Using Registration between Multi-Plane Fluoroscopic Images and CT Images

1.M.Kuga 2 Y.Yasuda, 1 N.Hata, 1 Y.Dohi
1.Graduate School of Information Science, The Univ. of Tokyo
2.Dept of Medical Bioengineering and Sports Medicine, Hokkaido Univ

Abstract: A high-precision navigation system for Anterior Cruciate Ligament(ACL) reconstruction is presented. In the system, 3D CT data is used to visualize the structure of bones and optical localizer is used to detect the position of femur, tibia and surgical tools. Since CT images are acquired preoperatively and markers are fixed to bones intraoperatively, their relative position has to be initialized. To achieve this initialization, 2D/3D registration method between CT model and X-ray images was developed. The registration is performed by minimizing the difference between contour lines. As ACL reconstruction requires precision, three X-ray images taken from different angles are used for the registration. Simulated registration shows the mean error to be less than 1.5mm.
Keywords: image-guided surgery, navigation, 2D/3D registration, X-ray fluoroscopy, CT


人工股関節全置換術における臼蓋リーミングのロボット手術支援の検討

○菅野伸彦1,西井孝1,三木秀宣1,小山毅2,高尾正樹1,吉川秀樹1,越智隆弘2
1.大阪大学大学院医学系研究科 器官制御外科学
2.ロボティクス治療学

Robot-assisted acetabular reaming for cup placement in total hip arthroplasty

Nobuhiko Sugano*, Takashi Nishii*, Hidenobu Miki*, Tsuyoshi Koyama**, Masaki Takao*,Hideki Yoshikawa*, TakahiroOchi**
Department of Orthopaedic Surgery, Osaka Univ. Graduate School of Medicine*
Department of Medical Robotics and Image Sciences, Osaka Univ. Graduate School of Medicine**

Abstract: Force transferred to bone phantom materials during hemispherical reaming by an experienced joint surgeon and speed of the reamer advancement were measured to develop a robot-assisted acetabular reaming system for total hip arthroplasty. The surgeon seemed to keep the force constant around 100N during reaming. Based on the data of reaming with a hand-held tool by the surgeon, robot-assisted force-feedback reaming in the direction of reamer advancement due to the elasticity of the rigid frame of work.
Keywords: Total Hip Arthroplasty, Robot-Assisted Acetabular Reaming, Navigation


内視鏡ロボットシステムのための術中ナビゲーション機能の開発

○服部麻木a, 鈴木直樹a, 林部充宏a, 鈴木薫之a, 大竹義人a, 炭山和毅b, 田尻久雄c, 小林進b
a.東京慈恵会医科大学高次元いよう画像工学研究所
b.東京慈恵会医科大学外科学講座
c.東京慈恵会医科大学内視鏡科

Development of an kmage guided function for an endoscopic robot system

Asaki hattori a, Naoki Suzuki a, Mitsuhiro Hayashibe a, Shigeyuki Suzuki a, Yoshito Otake a, Kazuki Sumiyama b, Hisao Tajiri c, Susumu Kobayashi b
a.Institute for High Dimentional Medical Imaging, The Jikei University School of Medicine , Tokyo , Japan
b.Department of Surgery, The Jikei University School of Medicine, Tokyo, Japan
c.Department of Endoscopy, The Jikei University School of Medicine, Tokyo, Japan

Abstract: We have development an endoscopic robot system that enables various surgical procedures in the gastric tubes using two manipulators. During robotic surgery, surgeons often miss targeted 3D loation or the direction of the endoscope's tip in an abdominal region. Therefore, we have developed an image guided function for the endoscopic robot system. This function uses two components:a magnetic 3D location sensor and a graphic work station.The magnetic 3D location sensor tracks the location and the direction of the tip of the endoscope. The graphic work station captures the endoscope's video image and superimposes the patient's organ models onto the image using measured values of the location sensor. In this paper, we will describe the system's overview and the result of an animal experiment that we performed using this system.
Keywords: image guided surgery, data fusion, endoscopic robot


PCプロジェクタとDVカメラを用いた術中での生体変形計測法の開発

○林部充宏*,鈴木直樹*,服部麻木*,鈴木薫之*,大竹義人*,中田典生*.小林進**,中村仁彦***
*東京慈恵会医科大学高次元医用画像工学研究所
**東京慈恵会医科大学外科学講座
***東京大学大学院知能機械情報工学専攻

Development of intraoperative 3D deformation measurement system for living body using PC projector and DV cameras

Mitsuhiro Hayashibe*,Naoki Suzuki*, Asaki Hattori*, Shigeyuki Suzuki*, Yoshito Otake*, Norio Nakata*, Susumu Kobayashi**, Yoshihiko Nakamura**:
*Institute of High Dimensional Medical Imaging, Jikei Univ. School of Med.
**Dept. of Surgery, Jikei Univ. School of Med.
***Dept.of Mechano-Informatics, Univ. of Tokyo

Abstract: Intra-operative navigation in which the target position is provided to help the intuitive understanding of surgical field has been studied and applied in each clinical area. Position measurement of surgical field is usually performed with a magnetic sensor or a marker type optical sensor. In the navigation of hard tissue such as bone , the measurement of several markers which are dispersedly located on the surface is enough to detect the position of the object. However, for the navigation of soft tissue such as skin and liver , a sensor which can detect the deformation of the object surface will be required. In this study , a geometrical pattern generated by a PC projector is captured by DV cameras from multiple angles. This system can be easily set up in the operation room and can visualize the 3D deformation and texture of the living body.
Keywords: 3D Deformation Imaging, Registration, Navigation


医用断層画像オーバーレイシステムも画像統合に関する研究
−画像の簡易キャリブレーションツールの開発−

○松家大介1,正宗賢2,石川達也3,村垣善浩4,杉浦誠3,伊関洋4
1.東京電機大学理工学研究科
2.東京電機大学理工学部
3.所記念病院
4.東京女子医科大学大学院先端生命医科学研究所

Slice image overlay system-the instant calibration tool for image registration-

○D.Matsuka1, K.Masamune2, T.Ishikawa3, Y.Muragaki4, M.Sugiura3, H.Iseki4
1.Graduate School of Sciences and Engineering, Tokyo Denki University
2.School of Sciences and Engineering , Tokyo Denki University
3.Tokoro Memorial Hospital
4.Graduate School of Medicine, Tokyo Women's Medical University

Abstract: Many types of medical images are used for neurosurgical navigation system, however, surgeon often encounter the difficulties to have a precise registration between pre-operative images and the patients. To solve this problem , we proposed to apply " augmented reality system" with a simple display device . The display device comprises a 5.6 inch LCD flat panel display, a half mirror, and a passive positioning maker to detect the spatial position in the operating room. Through the half mirror, surgeon can observe the real patient and reflected image of the display, on which the navigation image are described similtaneously. By this navigation system, the slice image is shown in appropriate positions and theexact size. In this paper, we devised the new calibration technique which instantly combines three dimentional MRI image and natural view space . This device will be useful using intra-operative images such as interventional MRI.
Keywords: surgical navigation, augmented reality , half mirror


光磁気ハイブリッド三次元位置センサによる鏡視下手術ARナビゲーションの開発−実時間磁場歪み補正のin vivo 精度検証−

○小西晃造a, 橋爪誠a, 中本将彦b, 山口鉄蔵b, 佐藤嘉伸b, 田村進一b, 前原喜彦c
a.九州大学大学院医学研究院災害・救急医学,c.同消火器・総合外科
b.大阪大学大学院医学研究科多元的画像解析分野

Augmented Reality Navigation System for Laparoscopic Surgery

K.Konishi a, M.Hashizume a, M.Nakamoto b, T.Yamaguchi b, Y. Sato b, Y.Maehara c
a.Department of Disaster and Emergency medicine, c. Surgery and Sciences, Graduate School of Medical Sciences, Kyushu University
b.Division of Interdisciplinary Image Analysis, Osaka University Graduate School of Medicine

Abstract: We have developed an augmented reality navigation system for laparoscopic surgery so far. This system measures the 3D position at the tip of ultrasound probe in abdominal cavity . Although a magnetic tracker is suitable for this purpose, their accuracy is affected by metallic objects such as operating equipments and tables. We have recently proposed the method of precise " real-time" distortion correction of magnetic fields. In this paper, we evaluated the accuracy and validity of this system by the in vivo experiment.
Keywords: AR navigation, distortion correction, 3D-US


内視鏡ナビゲーションにおける拡張現実感表示の誤差解析

○山口鉄蔵a, 中本将彦a, 佐藤嘉伸a, 橋爪誠b, 菅野伸彦c, 田村進一a
a.大阪大学大学院医学系研究科多元的画像解析学分野
b.九州大学医学部付属病院先端医工学診療部
c.大阪大学大学院医学系研究科臓器制御医学講座

Error Analysis for Endoscopic Augmented Reality Navigation System

T.Yamaguchi a, M.Nakamoto a, Y.Sato a, M.Hashizume b, N.Sugano c, S.Tamura a
a.Division of Interdisci;oinary Image Analysis, Osaka University Graduate School of Medicine, Osaka, Japan
b.Department Center for the Integration of Advanced Medicine and Innovative Technology, Kyushu University, Kyushu, Japan
c.Department of Orthopedic Surgery, Osaka University Graduate School of Medicine, Osaka, Japan

Abstract: Augmented reality (AR) system for rigid endoscopic surgery have been widely studied for clinical application . We analyzed superimpose accuracy incorporating registration, camera calibration, and tracking errors, which are components of a total AR system. Laparoscopic and arhroscopic AR systems were analyzed in this study . We investigated the dependency of the superimpose error on distance from camera coordinate origin to coordinate origin of rigid body. In case of laparoscope , when distance from camera coordinate origin to coordinate origin of rigid body is 500 mm , the error of superimpose was 4.7 pixels. In case of arhroscope, when distance from camera coordinate origin to coordinate origin of rigid body was 300 mm, the superimpose error was 3.7 pixels.
Keywords: surgery navigation system, registration error, camera calibration, accuracy validation.


Motion sensor を用いた腹腔鏡手術用3DCT simulation およびReal time navigation surgery の有用性について

○瀧口修司1, 関本貢嗣1, 宮田博志1, 藤原義之1, 安田卓司1, 矢野雅彦1, 堀 雅敏2, 村上卓道2, 中村仁信2, 桝本潤3, 佐藤嘉信3, 田村進一3, 門田守人1
1.大阪大学大学院病態制御外科
2.同放射線科
3.同多元画像解析分野

Impact of preoperative virtual laparoscopy and intraoperative navigation system using real time rendered 3D CT images reconstructed as laparoscopic view

S.Takiguchi1, M.Sekimoto1, H.Miyama1, Y.Fujiwara1, T.Yasuda1, M.Yano1, M.Hori2, T.Murakami2, H.Nakamura2, J.Masumoto3, Y.Sato3, S.Tamura, M.Monden1
1.Department of Surgery and Clinical Oncology
2.Department of Radiiology
3.Department of Medical Robotics and Image Sciences

Abstract: Introduction: Resent dvancement of laparoscopic surgical technology allowed us to perform advanced high level surgery such as lymph node dissection for malignancy. Deep understandings of the anatomy would play an important role to perform a complicated lymph node dissection. We developed a novel imaging information system for laparoscopic surgery presenting 3D CT angiography reconstructed as laparoscopic view . We developed a new soft for Windows OS PC, which provided us real time 3D angiographic image synchronized with intraoperative endoscopic motion using a motion sensor. In this paper we described impact of our new laparoscopic virtual reality simulator and navigation system. Methods: Enhanced multi detector CT rendered by a PC (OS : Windows XP) can provide us 3D angiography reconstructed laparoscopic view . This PC connected to the motion sensor, which was mounted on an endoscope and could detect an angle of direction of laparoscopy, can synchronize these images to the direction of laparoscopy . A submonitor controlled by Endo alpha system (Olympus. Co, Japan) projected these images beside a main monitor. The operator navigated the surgery with reference to this monitor during lymph node dissection real timely. This system also can be used as preoperative virtual reality simulation. Result: Our new simple navigation system will be new weapon for the safety laparoscopic surgery .
Keywords: computer aided surgery, laparoscopy, navigation surgery


術中MRI・組織弾性イメージを用いたハイブリッドナビゲーションシステム

○谷口拡樹a,c, 伊関洋a,b, 村垣善浩a,b, 村松剛c, 小島康志d, 紫雲俊美d, 椎名毅e, 新田尚隆e, 山川誠e, 平孝臣b, 堀智勝b, 高倉公朋a
a.東京女子医科大学大学院先端生命医科学研究所先端工学外科学
b.東京女子医科大学脳神経センター脳神経外科
c.日立メディコ
d.瑞穂医科工業
e.筑波大学電子・情報工学系

Hybird Navigation System using Image Fusion of Intraoperative MRI and Ultrasound Elasticity Imaging

Hiroki Taniguchi a,c, HIroshi Iseki a,b, Yoshihiro Muragaki a,b, Takeshi Matsumura c, Yasushi Kojima d, Toshimi Shiun d , Tsuyoshi Shiina e, Naotaka Nitta e, Makoto Yamakawa e, Takaomi Taira b, Tomokatsu Hori b, Kintomo Takakura a
a.Tokyo Women's University, Faculty of Advanced techno-surgery (FATS),Institute of Advanced Biomedical Engineering and Science
b.Department of Neurosurgery, Neurological Institute .
c.Hitachi Medical.
d.Mizuho Co Ltd.
e.Tsukuba University

Abstract: Intraoperative MRI is very important modality especially for glioma resection in neurosurgery, since the tumor status can be evaluated interactively by updated MR images taken whenever necessary. But it is difficult to identify only a brain tumor from among unclear border between brain tumors and normal tissues. Consequently for the purpose of identifying only a brain tumor by utilizing different elasticity between brain tumors and normal tissues, we have developed hybrid navigation system using image fusion of intraoperative MRI and ultrasound elasticity imaging.
Hybrid diagnosis combined morphologic images and elasticity images may maximize the diagnostic yield compared to the conventional diagnosis using only a morphologic image.
Keywords: hybirid navigation system, image fusion, intraoperative MRI, elasticity imaging


異種情報インテグレーションによる情報誘導外科の展開

○村垣善浩a, 伊関洋a,b, 丸山隆志b, 中村亮一a, 林基弘a,b, 久保長生b, 堀智勝b, 高倉公朋a
a.東京女子医科大学大学院先端生命医科学研究所先端工学外科分野
b.東京女子医科大学脳神経外科

Advanced Information-guided Surgery by Integration of Data from Different Modalities

Y.Muragaki a, H.Iseki a,b, T.Maruyama b, R.Nakamura a, M.Hayashi a,b, O.Kubo b, T.Hori b, K.Takakura a
a.Department 1, Institution 1,Tokyo,Japan
b.Department of Neurosurgery, Tokyo Women's Medical University, Tokyo, Japan

Abstract: We have developed an operating system that provides several kinds of objective information for neurosurgery (intelligent operating theater).
This system mainly detects anatomical, functional, and histological information obtained by intraoperative MR images/navigation, the mapping/ monitoring, and frozen setion/5ALA, respectively. The intraoperative information contributed 91% of the resection rate and 13% of the complication rate in infiltrative glioma cases. To improve the surgical results, we need not only to improve the quality of each information, but also to integrate the different kinds of information. We here report the data integration system via the navigation to help the decision making process in the surgical procedures.
Keywords: glioma, resection, navigation system


Open MRI 下脳外科手術におけるナビゲーションシステムの精度及び操作性向上に関する研究

長島義昭1, 廣瀬佐智雄1, 鈴川浩一2, 苗村潔5, 高信英明4, 村垣善浩3, 伊関洋3, 梅津光生1, 高倉公朋3
1.早稲田大学大学院理工学研究科・生命理工学専攻
2.インフォコム株式会社
3.東京女子医科大学大学院先端生命医科学研究所・先端工学外科学分野
4.工学院大学工学部機械システム工学科

Improvement of a navigation system for the neurosurgery in the intraoperative MRI-equipped operating theater-

Y.Nagashima1, S.Hirose1, H.Suzukawa1,2, K.Naemura3, H.Takanobu4, Y.Muragaki3, H.Isekie, M.Umezu1, K.Takakura3
1.Dept. Integrative Bioscience and Biomedical Engineering, Waseda University
2.Infocom Co.Ltd.
3.Faculty of Advanced Techno-Surery, Institute of Advanced Biomedical Engineering & Science, Tokyo Women's Medical University
4.Dept. of echanical Engineering, Kogakuin University
5.Tokyo University of Technology

Abstract: Final goal of this research is to achieve a perfect extraction of malignant brain tumor with Open MRI system, while preserving a brain function. Followings might be major reasons for poor accuracy or extended surgical time; 1) Technique is difficult to obtain an ideal condition using present pointer for registration. 2) Training is required to search an exact position of each marker on the MRI image. Authors developed a reflect ball marker that can solve the above problems. This newly designed marker has the combined function of conventional operation marker with function of reflective ball can be recognized by optical position measuring equipment. Then, automatic registration become possible to eliminate 1) and 2). Consequently, navigation preparation time was dramatically decreases, and navigation accuracy became much improved.
Keywords: registration, Reflective ball marker, Navigation preparation time , Navigation accuracy


術中オープンMRIによる術中拡散テンソルナビゲーションシステムの開発

○小澤紀彦a,b, 伊関洋a,c, 村垣善浩a,c, 中村亮一a, 白川洋b, 渡部滋b
a.東京女子医科大学大学院先端生命医科学系専攻先端工学外科学分野
b.鞄立メディコMRIシステム本部
c.東京女子医科大学脳神経センター脳神経外科

Development of the Navigation System employing Updated Diffusion Tensor Imaging using Intraoperative Open MRI

N.Ozawa a,b, H.Iseki a,c, Y.Muragaki a,c, R.Nakamura a, H.Shirakawa b, S.Watanabe b
a.Faculty of Advanced techno-surgery (FATS) Institute of advanced Biomedical Engineering & Science(ABME&S) Graduate School of Medicine (R&D) Tokyo Women's Medical University, Tokyo, Japan
b.MRI System Division, Hitachi Medical co, Chiba, Japan
c.Dept. of Neurosurgery, Neurological Institute(Clinicaldivision) Tokyo Women's Medical University, Tokyo, Japan

Abstract: Preoperative diffusion tensor imaging obtained by using 1.5T MRI makes it clear that tumor's position vis-a-vis pyramidal tract in surgical removal of a malignant brain tumor which is close to the pyramidal tract. But it can't be used for operating navigation image because brain parenchyma movesand changes the shape after the tumor has been removed step by step . Our aim is to develope the navigation system employing updated diffusion tensor imaging using 0.3 T intraoperative open MRI to complete removal of a cerebral tumor. Fine adjustment of static magnetic field, conformity assessment of diffusion tensor imaging of the conventional coil for operations , study of diffusion tensor imaging parameters with a diagnostic head coil, diffusion tensor analysis and evaluation were done in the open MRI operating theater (AIRIS II 0.3 T, Hitachi Medical co.). In consequence, homogeneity of static magnetic field has improved . Because the conventional coil for operations did not fit for diffusion tensor imaging, it needs to be improved. The diffusion tensor imaging for volunteer enabled the white matter fiber such as pyramidal tract and corpus callosum to be displayed.
Keywords: intraoperative MRI, intraoperative diffusion tensor imaging, real-time update navigation


リアルタイムMRガイド下インターベンション支援ソフトウェアの開発

○森川茂廣a, 犬伏俊郎a, 佐藤浩一郎b, 出村公一b, 来見良誠b, 仲 成幸b, Hasnine A Haque c
滋賀大学 a. 分子神経生物学センター b. 外科学講座 c. GE横河メディカルシステム

Development of Software Tools to Assist Realtime MR-Guided Interventional Procedures.

S.Morikawa a, T.Inubushi a, K.Sato b, K.Demura b, Y.Kurumi b, S.Naka b, H.A. Haque c
a.Molecular Newroscience Research Center ,and Dept of Surgery, Shiga University of Medical Science , Ohtsu, Japan
c.GE Yokogawa Medical systems, Hino, Japan

Abstract: Real - time MR images are quite useful in image-guided interventional procedures, but they have some limitations. For the fast image acquisition, T1-weighted SPGR images are usually utilized for this purpose. Because of the limited acquisition time of 2-3 seconds, the image quality and contrast are not always satisfactory. Sometimes, T2-weighted contrast and multi-slice acquisition are required for the accurate image navigation in the 3-dimentional space. To slove these problems and to assist real-time MR-guided interventional procedures, we have developed two software applications, MRNavi and ScoutPlane. The MRNavi utilized high-resolution preoperative images in combination with real-time MR images for the navigation in 3-dimensional space. It can control the MR scanner and can change acquisition parameters between needle tracking and MR temperature monitoring. The ScoutPlane can control multislice acquisition interactively while running the MR scanner. It has a capability to acquire, to calculate and to display multi-planar MR temperature maps. These two applications remarkably increased the feasibility of MR -guided interventional procedures.
Keywords: MR-guided intervention, Real-time MR images, interactive image guidance.


ナビゲーション手術の現状−全国主要施設耳鼻咽喉科アンケート結果より−

○石政 寛,竹村博一,村田英之,鈴鹿有子,友田幸一
金沢医科大学耳鼻咽喉科

The Application of Introperative Navigation System-A Questionnaire Survey in Otolaryngologists in Japan

H.Ishimasa, H.Takemura, H.Murata, Y.Suzuka, K.Tomoda
Department of Otolaryngology, Kanazawa Medical University

Abstract: Navigation system has been introduced into Otolaryngology for more than 10 years, during which various kinds of machines have been developed. It has been accepted by most of the Otolaryngologists because of its usefulness which has been reported in the literatures. Meanwhile, further efforts are required to improve the functions for clinical use.
A questionnaire survey was carried out in departments of Otolaryngology of 202 major hospitals in Japan, which aimed at the indication, the advantages and disadvantages, troubles occurred in use and corresponding measures adopted, further, expectation on the navigation system, and in what degree this system has been applied as an intraoperative guidance as well as in clinical education. Here we would like to report the results of this questionnaire survey.Finally, we would like to thank all the Otolaryngologists who have contributed to this questionnaire survey.
Keywords: Navigation system, Questionnaire Survey, Otolaryngology


脳血管内腔を再現した手術シュミレーション用立体モデル

○池田誠一a, 新井史人a, 福田敏男a, 根来眞b, 高橋郁夫c
a.名古屋大学
b.藤田保健衛生大学
c.安城更生病院

An In Vitro Lithe Model of Individual Cerebral Artery for Neurosurgical Simulation

S.Ikeda a, F.Arai a, T.Fukuda a, M.Negoro b, I . Takahashi c
a.Department of Micro System Engineering , Nagoya University, Nagoya, Japan
b.Department of Neurosurgery, Fujita Health University, Toyoake, Japan
c. Department of Neurosurgery, Anjo Kosei Hospital, Anjo, Japan

Abstract: An in vitro Lithe model replicating individual human cerebral artery for intravascular neurosurgical simulation, preclinical testing, and testing of medical devices is presented. This anatomically accurate arterial model is constructed using individual information obtained by medical imaging. With its soft membranous structure having some physical properties close to the value of arterial tissue, realstic surgical simulation accompanied with deformation of arterial structure is realized . We also present a composite arterial model reproducing also the surrounding soft tissues, exiting around the cerebral artery, in addition to the membranous arterial structure. As the presented arterial model is compatible with current major imaging modalities such as CT, MRA and TCD , it should prove useful for a wide range of applications, such as hemodynamic study and radiological investigations as well as surgical simulations.
Keywords: medical image , vascular model, apid prototype


レーザー光2平面交差による直線刺入術具誘導方式の理論的有効範囲解析

○山本宗主1,2, 中島義和2,1, 佐藤嘉伸2,1, 笹間俊彦3, 小山毅4, 田村裕一5, 桃井康行6, 菅野伸彦4, 米延策雄5, 吉川秀樹4, 佐久間一郎7, 越智隆弘8,9,田村進一2,1
1.大阪大学基礎工学部情報科学科
2.大阪大学大学院医学系研究科多元的画像解析分野
3.鳥取大学工学部知能情報工学科
4.大阪大学大学院医学系研究科器官制御外科学講座
5.国立大阪南病院
6.株式会社日立製作所
7.東京大学大学院新領域創成科学研究科
8.国立相模原病院
9.大阪大学大学院医学系研究科ロボティックス治療学分野

Theoretical analysis of available range in alignment procedure for linear surgical tools using projection of interesecting two laser planes

H.Yamamoto1,2, Y.Nakajima2,1, Y.Sato2,1, T.Sasama3, T.Koyama4, Y.Tamura5, Y.Momoi6, N.Sugano4, K.Yonenobu5, H.Yoshikawa4, I.Sakuma7, T.Ochi8,9, S.Tamura2,1
1.Department of Information Science , Osaka University
2.Division of Interdisciplainary Image Analysis, Osaka University Graduate School of Medicine
3.Department of Information and Knowledge Engineering Faculty of Engineering Tottori University
4.Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine
5.Osaka Minami National Hospital
6.Hitachi, Ltd
7.Department of Integrated Biosciences Graduate School of Frontier Science, University of Tokyo
8.National Sagamihara Hospital
9.Division of Robotic Therapy, Osaka University Graduate School of Medicine

Abstract: In previous work, we have developed a direct indication device of the navigation information for a surgical tool position and orientation by using an intersection line of dual laser beam plane. Although it was actually applied hip surgeries and showed the effectiveness, it was actuality that the rearrangement of laser devices was occasionally disturbed the surgery because of the calibration of the laser device positions. To escape the intra-operative calibration, we propose a new solution of the calibration-free laser guidance device which is rigidly equipped with a three-dimensional (3-D)localizer. In this paper, we theoretically describe the relation between the geometries of the devices and guidance information indicated on the side of a surgical tool . The results of available space analysis of the system are also shown.
Keywords: augmented reality, laser projection, surgical navigation, orientation guidance, accuracy validation


MRI対応穿刺治療支援モジュラー型ナビゲーションロボットの開発に関する研究

○長能弘明a, 正宗賢a, 伊関洋b, 中島勧c

MRI Compatible Modular designed navigation robot for needle screw insertion

a.Hiroaki NAGANOU,a.Ken MASAMUNE, b.Hiroshi ISEKI, c.Susumu NAKAJIMA
a.School of Science and Engineering , Tokyo Denki University, Saitama , Japan
b.FATS,Tokyo Women's Medical University, Tokyo, Japan
c.Dept. of Medicine, the University of Tokyo, Tokyo, Japan

Abstract: Recent advances of the interventional MRI (surgery in the Open MRI) proceed more safe and assured minimally invasive surgery using MR images acquired during operation. To achive more precise, fast and safety therapy, the introduction of a surgical robot is one solution with the combination of image information, however, a mere introduction of the conventional robot is prohibited because it will probably disarrange the strong magnetic field in MR environment and cause image distortions. In this study, we are presenting 2DOF small MRI-Compatible surgical robot, which is made of non-ferromagnetic materials. We also evaluate the manipulator in MR environment , and conclude that this actuator have enough positioning accuracy and has almost no influence to the image quality.
Keywords: MRI compatible actuator, surgical robot


MRガイド下肝腫瘍マイクロ波凝固療法における正確な穿刺のための工夫

○佐藤浩一郎*,来見良誠*,仲成幸*,出村公一*,谷徹*,森川茂廣**,犬伏俊郎**,Hasnine A Haque***
*滋賀医科大学外科
**分子神経科学研究センター
***GE 横河メディカルシステム
Koichiro Sato*, Yoshimasa Krumi*, Shigeyuki Naka*, Koichi Demura*, Tohru Tani*,Shigehiro Morikawa**, Toshiro Inubushi**, Hasnine A Haque***
*Department of Surgery, and **Molecular Neuroscience Research Center, Shiga Univeristy of Medical Science, Ohtsu, Japan, and ***GE-Yokogawa Medical Systems, Hino, Japan

Abstract: In order to insert the electrode for microwave ablation into the tumor accurately , several techniques were utilized . The tumor area was shown as a colored 3-dimensional volume. Usually repeated punctures and ablations were required for the complete treatment of the tumor. The already treated part was indicated by foot-ball shaped " Foot Prints " and the remaining parts of the tumor to be treated were shown clearly. Since the effective coagulated area by the microwave ablation is 20 mm in diameter, 20 mm thick cylinder was displayed depending on the direction of the puncture route. The direction of the needle was adjusted to include the target in the cylinder. After careful adjustment of the direction, the planned lane for the puncture was imprinted to the preoperative 3-dimensional volume data. From the 3D data including the lane, reformatted images corresponding to the real -time MR images were constructed . It had been difficult to detect the displacement of the needle during puncture in the real-time images controlled by the needle position. Using these techniques, accurate navigation could be carried out by simple tracking of the lane in the reformatted images and effective microwave ablation of liver tumors was accomplished.
Keywords: Cojputer-aided MR guided ablation and Lane guide navigation


VGLとDirectShow ライブラリを用いたCT/MRIと内視鏡画像のリアルタイム統合レンダリング

○山内康司
産業技術総合研究所 治療支援技術グループ

Real-time integrated rendering of CT/ MRI and endoscopic images using VGL and DirectShow libraries

Yasushi Yamauchi
Surgical Assisut Technology Group , National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan

Abstract: [Objective] Minimally invasive surgery requires variety of imaging modalities, including endoscope and CT/MRI . In most cases these images are presented as 2D in separated views. This study proposes real-time integration and rendering method for intraoperative medical images. [Methods] Three types of medical images, volume data, optical images (ex. endoscope ) and instrument data are subject to integration, and each image needs different rendering methods . VGL graphics library has capability of volume rendering mixed with OpenGL geometry. DirectShow class library supports capturing of optical video images. [Results] The graphics performance was sufficient for intraoperative use (15.2 fps) on a PC (Xeon 2.8 GHz) with CT (256x256x101 voxels), endoscope and instrument data. A delay was slightly observed in endoscopic view, though . [Conclusion]VGL and DirectShow realized three- dimensional integration and real-time rendering of volume data, optical images and instrument data on standard PCs.
Keywords: image integration, volume rendering, VGL, DirectShow


Open surgery を対象としたData fusion システム用画像提示デバイスの開発

○大竹義人a, 鈴木直樹a, 服部麻木a, 鈴木薫之a, 林部充弘a, 小林進b
a.東京慈恵会医科大学高次元医用画像工学研究所
b.東京慈恵会医科大学外科学講座

Development of Image Display Devices for the Data Fusion System at Open Surgery

○Yoshito Otake a, Naoki Suzuki a, Asaki Hattori a, Shigeyuki Suzuki a, Mitsuhiro Hayashibe a, Susumu Kobayashi b
a.Institute for High Dimensional Medical Imaging, Jikei Univ. Sch. of Med.
b.Department of Surgery, Jikei Univ.Sch. of Med.

Abstract: The data fusion system is a surgical navigation system, which enables surgeons to observe the inner body structure during surgery.
We have been developing several techniques or algorisms which are essential for the data fusion system. In this study, we focused on image display devices of the data fusion system specific for open surgery . We have developed two types of display devices which use two different types of mixed reality technique: a video see-through method and a floating window method. Our devices consist of a liquid-crystal - monitor attached to the ceiling -mounted articulating arm and a 3D optical tracking system.The monitor and the objective organ were registered by the optical tracking system, and the 3D inner body structure model reconstructed from CT or MRI images was displayed on the monitor during surgery. As for the floating window method, the head position of the surgeon was also registered preceding surgery and tracked by the optical sensor, so that the surgeon could observe from various points of view.In contrast, the video see-through method uses a small size video camera mounted on the back of the monitor in order to take the image from the same viewpoint as viewed by a surgeon. We validated the performance of these two devices by an experiment in the operating room.
Keywords: data fusion system, optical see-through, video see-through


脊椎instrumentation手術におけるコンピュータ支援術中計測システム

○田村裕一*, 米延策雄*, 中島義和**, 小田剛紀*, 菅野伸彦***, 佐藤嘉伸**, 田村進一**, 吉川秀樹***, 越智隆弘****
*   国立大阪南病院  整形外科
**  大阪大学大学院 多元的画像解析
*** 大阪大学大学院 器官制御外科学
****大阪大学大学院 ロボティク治療学 

Computer-assisted Intraoperative Measurement System for Spinal Instrumentation Surgery

Yuichi Tamura*, Kazuo Yonenobu*, Yoshikazu Nakajima**, Takenori Oda*, Nobuihiko Sugano***, Yoshinobu Sato**, Hideki Yoshikawa***, Takahiro Ochi****
* Department of Orthopeadic Surgery, Osaka Minami National Hospital
**Division of Interdisciplinary Image Analysis, Osaka University Graduate School of medicine
***Department of Orthopeadic Surgery, Osaka University Graduate School of medicine
****Division of Robotic Therapy, Osaka University Graduate School of medicine

Abstract: Correction or control of spinal alignment is one of the reasons for use of spinal instrumentation. However, there is no metod to visualize and track the three-dimensional (3-D) alignment of the operated spine segment during surgery. CT-based image guided surgery has enabled us to track and visualize the present 3-D position of the vertebra and surgical tools . In the most CT-based navigation systems, the vertebral motion is tracked by the dynamic reference frame, which was attached to the spinous process of the target vertebra. Therefore , using the dynamic reference frame as a motion tracker allows us to track the 3-D alignment of the operated vertebrae as well as the surgical tools under the guidance of computer navigation. In order to evaluate the 3-D alignment of spine segment, we have developed a novel intraoperative measurement system by using a CT-based navigation system for spinal instrumentation system. In each case, 3-D alignment of the operated spine segment was measured . This system allows us to monitor the alignment of fused segments and can be an effective and feasible tool for spinal fusion surgery.
Keywords: Spinal instrumentation, Navigation , Intraoperative measurement and Reporting system


5-Aminolevulinic Acid (5-ALA) を応用した術中脳腫瘍同定−半導体レーザーと光ファイバを用いた局所計測法−

○清水一秀1, 小林英津子1, 丸山隆志2, 村垣善浩2, 伊関洋2, 佐久間一郎1
1.東京大学大学院新領域創成科学研究科
2.東京女子医科大学大学院先端生命医科学研究所先端工学外科

Intraoperative detection of brain tumor using 5-Aminolevulinic Acid (5-ALA)
-study on point measurement sith a laser diode and an optical fiber-

1.K.Shimizu, 1.E.Kobayashi, 2.T.Maruyama, 2.Y.Muragaki, 2.H.Iseki, 1.I.Sakuma
1.Graduate School of Frontier Sciences, The University of Tokyo
2.Faculty of Advanced Techno-Surgery, Institue of Advanced Biomedical Engineering and Science, Graduate School of Medicine, Tokyo Women's Medical University

Abstract: In neurosurgery, tumor tissue most be removed as much as possible to prevent recurrence. We have studied on application of 5-Aminolevulinic Acid (5-ALA) as a tumor marker. 5-ALA biosynthetically induces a fluorescent substance called Protoporphyrin9 (Pp9).Pp9 is excited by blue or violet light and emits red fluorescence. Detection of the fluorescence can lead to precise removal of tumor. We introduced a blue-violet laser diode as an excitation light source and an optical fiber to collect the fluorescence. We aim to detect the fluorescence with high spatial resolution for better resection rate. To achive this purpose, we focused the laser on the surface of brain tissue to limit the area to generate fluorescence. In this paper, we made an optical phantom for brain tumor taking scattering coefficient into account. And also, we studied on the effect of focusing laser beam changing laser spot diameter. Our result shows that broadening of illuminated area will increase the intensity of collected fluorescence. On the other hand , it may impair the spatial resolution. In addition, our new optical phantom is highly useful for 5-ALA study, especially for experiments for demarcation of tumor boder.
Keywords: Neurosurgery, 5-ALA, 5-Aminolevulinic Acid, Protoporphyrin9, Point Measurement, Optical Phantom


自動セグメンテーションと3Dオプティカルフローを用いたMRI誘導下冷凍治療支援システムの開発

○中村亮一a, Kemal Tuncali b, Paul R. Morrison b, Stuart G. Silverman b, Ferenc A. Jolesz b, Gary P. Zientara b
a.東京女子医科大学先端生命科学研究先端工学外科学分野
b.Department of Radiology, Brigham & Women's Hospital and Harvard Medical School

Contorol System for MR-guided Cryotherapy ; Short term prediction of therapy boundary using Automatic Segmentation and 3D Optical Flow

R.Nakamura a, K.Tuncali a, P.R.Morrison, S.G.Silverman, F.A.Jolesz, G.P.Zientara b
a.Faculty of Advanced Techno-Surgery, Institute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University , Tokyo, Japan
b.Department of Radiology, Brigham & Women's Hospital and Harvard Medical School, MA, USA

Abstract: During cryotherapy, it is extremely useful for the interventionalist to have available intra-operatively a 3D iceball visualization in order to ensure the effectiveness and safety of the procedure. Additionally, it highly beneficial to provide the interventionalist with a best estimate of what will occur in near future so the progress of the procedure can be carefully controlled. That is, the aim is to provide a best estimate of how the iceball will grow and an estimate of the extent to which the target region and the tissues around it will be ablated .The quantitative analysis of ablation treatment is difficult during therapy due to the typically 2D representation of intro-operative MR image information, and the inhomogeneity of the iceball growth due to nearby vessels or other perturbing anatomy. Previously, we formally developed and evaluated a predictive method for estimating the extent and effectiveness of thermal therapies using 2D optical flow. In this study, we introduce a newly developed computerized control system for cryotherapy using 3D visualization and a 3D optical flow computation along with other novel software tools . Our new control system provides intra-operatively for the real-time and future-predicted quantitative assessments of the cryotherapy treatment. System evaluation and validation was performed using animal cryotherapy experiments data.
Keywords: MR-guided Therapy, Cryotherapy, Optical Flow, Segmentation


口腔領域CT像における金属修復物によるアーチファクト除去法

○荘村泰治1, 北條博一2, 楠本直樹1, 西田雅彦1, 若林一道1, Rungnapa Lowmunkong 1, 中村隆志1, 矢谷博文1, 高橋純造1
1.大阪大学大学院歯学研究科顎口腔機能再建学講座
2.大阪歯科大学口腔診断科

A Method of Removing Artifacts due to Metallic Dental Prostheses in Cranial Bone 3D CT Imaging

T.Sohmura1, H.Hojo2, N.Kusumoto1, M.Nishida1, K.Wakabayashi1, R.Lowmunkong1, T.Nakajura1, H.Yatani1, J.Takahashi1
1.Osaka University Graduate School of Dentistry, Div. of Oralmaxillofacial Regeneration
2.Osaka Dental University, Department of Oral Diagnosis

Abstract: CT images in the oral area are often disturbed by artifacts due to metallic dental prostheses, and valuable information on dental treatment, such as dentition, occlusion and maxillomandibular relation is often damaged . This study attempts to substitute the damaged dentition area of the cranial bone image with a dental cast model image obtained by CT . The position of the dental cast image was registrated to that of the cranial bone image using a devised interface that was composed of an occlusal bite and a marker plate made of gypsum.The damaged region in the cranial bone image was removed and substituted with the trimmed image of the dental cast. In the developed method, the image of dentition severely damaged by an artifact was successfully restored, and the image of stomatognathic system became clear.
Keywords: artifact, 3-D CT image, computer, dentistry


MRI 画像データによるハイドロキシアパタイト 頭蓋プレートの設計と臨床応用

○阿部慶太2,伊関洋1, 臼倉政雄1, 小河原善幸2, 小川哲朗2
1.東京女子医科大学脳神経センター
2.ペンタックス潟宴Cフケア事業部 ニューセラミックス事業部 開発部

Designing of Hydroxyapatite Clanialplate using MRI Image Date

○Keita Abe 2, Hiroshi Iseki1, Masao Usukura1, Yoshiyuki Ogawa2, Tetsuro Ogawa2

Abstract: Hydroxyapatite Implant for cranioplasty is designed by using computer-aided design and computer-aided machinery (CAD/CAM) technique based on CT data to prepare an accurately shaped implant . Recently , the perforamnce of CT scanner was remarkably advanced and put into practical use, permits higher image processing speed, however, patients were exposed to radiation. Therefore, We tried to design hydroxyapatite ceramic implant based on data from MRI .
Keywords: MRI, CT, hydroxyapatite, cranioplasty


自己参照型温度分布画像化法における位相不連続の補正法

○山本洋介1, 熊本悦子3, Bilgin Keserci4, 原田泰樹5, 国領大介5, 黒田輝1,2
1.東海大学大学院工学研究科
2.先端医療振興財団映像研究部
3.神戸大学工学部
4.CE横河メディカルシステムズ
5.神戸大学大学院自然科学研究科

Method of Compensating the Phase Discontinuity in a " Self-Reference " Type Temperature Distribution Imaging

○Yousuke Yamamoto1, Daisuke Kokuryo 5, Etsuko Kumamoto3, Bilgin Keserci4, Daiki Harada5, Kagayaki Kuroda1,2
1.Graduate School of engineering , Tokai University, Hiratsuka, Japan
2.Department of Image-based Medicine, Institute of Biomedical Research and Innovation, Kobe, Japan
3.Faculty of Engineering , Kobe University
4.GE Yokogawa Medical Systems, Imaging Application Tech Center, Tokyo, Japan
5.Graduate School of Science and Technology, Kobe University

Abstract: Magnetic resonance imaging (MRI) is known to be the only modality for non-invasive imaging of internal organ temperature under thermal therapics. The thermal change in the phase evolution of the macroscopic magnetization vector has been obtained as the temperature indicator in the conventional method by subtracting the phase at each voxel before heating from that after heating. In the moving organ such as liver , however, the voxel-by-voxel phase subtraction process becomes problematic because of the change in the tissue position and the magnetic flux.To overcome this problem, we have proposed a " self-referenced " method, in which the reference phase value without thermal change is estimated based on the spatial continuity of the phase distribution around the treated tissue region. Our preliminary experimental results demonstrated that the method is effective and viable for imaging liver temperature in vivo. The preprocessing for the compensation of phase wrapping was effective when such phase wrapping was inside the phase field to be used for the phase estimation.
Keywords: MRI, temperature, phase, motion, self-referenced


自己参照型差分法を用いたMRI温度分布計測における位相推定法の最適化

○国嶺大介*,黒田輝**,熊本悦子***,原田泰樹*,Biligin Keserci ****, 藤井進***
*神戸大学大学院自然科学研究科
**(財)先端医療振興財団映像医療研究部
***神戸大学工学部
****GE横河メディカルシステムズ

Optimization of phase estimation process in MR Temperature Imaging Using the Self-Referenced Phase Subtraction Method

○Daisuke Kokuryo*, Kagayaki Kuroda**, Etsuko Kumamoto***, Daiki Harada*, Biligin Keserci****, Susumu Fujii***
*Graduate School of Science and Technology, Kobe University
**Department of Image-based Medicine, Institute of Biomedical Research and Innovation
***Faculty of Engineering , Kobe University
****GE Yokogawa Medical Systems, Ltd, Tokyo, Japan

Abstract: Magnetic resonance imaging (MRI) has capability of imaging temperature change during thermal therapies. To date , the conventional way, in which temperature change distribution is obtained by taking the voxel-by-voxel phase difference of water proton system at different temperature states, has been used. In imaging temperature distribution in an abdominal organ such as liver, the subtraction process suffers remarkable effect of respiratory motion. A new temperature imaging method called " self-referenced " method, in which temperature difference is obtained by estimating the fase distribution before temperature change based on the smoothness and continuity of the phase field around the heated region, was proposed. Two different strategies of the phase interpolation were compared. The approach to estimated the phase distribution using the real and imaginary part distributions around the region of interest was superior to the approach using the phase image directry: the error in the former was around 5℃and was , at most , 10% of that in the letter even when the conventional method completely lost the temperature information due to the significant effect of the organ motion.
Keywords: MRI, temperature imaging, phase subtraction, interpolation, error


3D-MR volume registration の膝関節への応用とその精度

○高尾正樹a, 菅野伸彦a, 西井孝a, 三木秀宣a, 小山毅b, 佐藤嘉伸c, 田村進一c, 吉川秀樹a, 越智隆弘b
a.大阪大学大学院医学系研究科器官制御外科学
b.大阪大学大学院医学系研究科ロボティクス治療学
c.大阪大学大学院医学系研究科多元的画像解析学

Accuracy evaluation of 3D-MR volume registration for knee joints

Masaki Takao a, Nobuhiko Sugano a, Takashi Nisii a, Hidenobu Miki a, Tsuyoshi Koyama b, Yoshinobu Sato c, Shinichi Tamura c, Hideki Yoshikawa a, Takahiro Ochi b
a.Department of Orthopedic Surgery, Osaka University Graduate School of Medicine, Osaka , Japan
b.Division of Robotic Therapy, Oska University Graduate School of Medicine, Osaka, Japan
c.Division of Interdisciplinary Image Analysis , Department of Medical Robotics and Image Sciences, Osaka University Graduate School of Medicine, Osaka, Japan

Abstract: Image registration is a comp utational process for matching 2 different images. To apply this method for longitudinal evaluation of lesions around knee joints, we investigated the accuracy of three-dimentional (3D) MR volume registration for both distal femur and proximal tibia and fibula. Five phantoms of the knee joint were made from embalmed cadaveric knee joints. Each phantom was MR imaged in 9 positions, with 8 markers attached to the distal femur and the proximal tibia. Eight MR images were registered to the remaining reference image , resulting in total 40 sets of registration. The accuracy of registration was evaluated by measuring the 3D displacement of the markers of the distal femur and proximal tibia were 0.44 ±0.14 mm (SD) and 0.63 ±0.36 mm(SD), respectively . These were smaller than the voxel size (1.32x 1.32x1.5mm). The translation error was also less than the voxel size, and the rotation error was less than 1°. This method is apparently useful for precise evaluation of lesion size change around knee joints.
Keywords: magnetic resonance imaging; image registration; knee joint


MRIを用いた膝関節面下肢荷重軸軌跡を求めるシステムの構築

川上秀夫*,菅野伸彦**,米延策雄***,吉川秀樹**,越智隆弘*,服部麻木****,鈴木直樹****
*大阪大学大学院医学系研究科先端応用医工学講座
**大阪大学大学院医学系研究科器官制御外科学講座
***国立大阪南病院
****東京慈恵医科大学総合医科学研究センター高次元医用画像工学研究所

MRI Based System to Demonstrate the Locus of the Dynamic Loading Axis on the Knee during gait

Hideo Kawakami*, Nobuhiko Sugano**, Kazuo Yonenobu***, Hideki Yoshikawa**, Takahiro Ochi*,Asaki Hattori****, Naoki Suzuki****
*Department of Medical Robotics and Image Sciences, Osaka Univ. Graduate School of Medicine
**Department of Orthopaedic Surgery, Osaka Univ. Graduate School of Medicine
***Department of Orthopaedic Surgery, Osaka-Minami National Hospital
****Institute for High Dimensional Medical Imaging, Jikei Univ. School of Medicine

Abstract: We developed a CT-based program to demonstrate the locus of the dynamic loading axis on the proximal tibia joint surface during gait using CT images. We added an option to reconstruct patient specific bone models of the lower limbs using MR images instead of CT images. Purpose of this study is to demonstrate how the option wouks. MR images of whole lower limb were taken with ball markers of gait analysis. Walking data of healty volunteer was obtained using Vicon motion analysis system. The MR sequence was 3D Fast SPGR , TE In phase (4.2msec), TR9.0msec, Flip angle 15deg, Band width 31.25 kHz, FOV 42cm , Thickness 2mm, Location per slab 64, Matrix 256*256, 1NEX , 1min 27sec/slab. MR images of whole lower limb were obtained by connecting the seven parts of the lower limb in 3D . The 3D surface models of the femur, tibia, and ball markers were reconstructed from axial MR images. The ball marker positions between MR images and gait analysis were matched . The relative positions of the femur and tibia during gait were calculated. The locus of the dynamic loading axis that the loading axis of the lower limb moved along the proximal tibia joint surface during gait was showed .
Keywords: locus of the dynamic loading axis on the knee, MRI based simulation system


膝関節面における下肢荷重軸軌跡を求めるシステムの精度検証

川上秀夫*,菅野伸彦**,米延策雄***,吉川秀樹**,越智隆弘*,服部麻木****,鈴木直樹****
*大阪大学大学院医学系研究科先端応用医工学講座
**大阪大学大学院医学系研究科器官制御外科学講座
***国立大阪南病院
****東京慈恵会医科大学総合医科学研究センター高次元医用画像工学研究所

Accuracy of gait analysis system for assessment of Dynamic Loading axis of the Knee

Hideo Kawakami*, Nobuhiko Sugano**, Kazuo Yonenobu***, Hideki Yoshikawa**, Takahiro Ochi*, Asaki Hattori****, Naoki Suzuki****
*Department of Medical Robotics and Image Sciences , Osaka Univ.Graduate School of Medicine
**Department of Orthopaedic Surgery, Osaka Univ. Graduate School of Medicine
***Department of Orthopaedic Surgery, Osaka-Minami National Hospital
****Institute for High Dimensional Medical Imaging, Jikei Univ. School of Medicine

Abstract: The purpose of this study was to assess the accuracy of gait analysis system for assessment of Dynamic Loading axis of the Knee. This system uses force plate data, CT skeletal structure data and motion capture data ( obtained using an infrared position sensor). The relative positions between bones and markers were used to calculate skeletal model movement based on movement of the markers. The locus of the dynamic loading axis on the knee joint was defined as the line that the loading axis of the lower limb moved along the proximal tibia joint surface.
To assess the accuracy of this system, open MRI was used to evaluate positions of skin markers against bones in 6 healty volunteers. The mean value of measurement error for opint locations on the locus was within 2.3±1.4(mean±SD)% of medial compartment joint width of the knee joint in the lateral direction, and within 19±9.7 % of the anterior half of anteroposterior joint width in the anteroposterior direction. This system can provide clinically useful information for evaluation of the dynamic loading axis on the knee joint surface.
Keywords: locus of the dynamic loading axis of the knee, accuracy of gait analysis system , open MRI


気管支鏡カメラ動き推定における画像間類似度の比較・検討

○圓城寺努1, 出口大輔1,北坂孝幸1, 森健策1, 末永康仁1, 長谷川純一2, 鳥脇純一郎2,
1.名古屋大学大学院情報科学研究科
2.中京大学情報科学部

Study on comparison of similarity measures between real and virtual bronchoscopic images in bronchoscopic camera motion estimation

○Tsutomu Enjouji1, Daisuke Deguchi1, Takayuki Kitasaka1, Kensaku Mori1, Yasuhito Suenaga1, jun-ichi Hasegawa2, Jun-ichiro Toriwaki2
1.Graduate school of Information Science, Nagoya University
2.School of Computer and Cognitive Science, Chukyo University

Abstract: This paper shows the results of performance comparison of two similarity measures, mean squared error (MSE) and normalized mutual information(NMI) , for bronchoscope tracking based on image registration between real and virtual bronchoscopic images.
Video tracking performance of MSE and NMI were examined for five cases of bronchoscopic video frames and chest X-ray CT images . The experimental results indicated that NMI was more sensitive than MSE to the difference of lighting conditions between real and virtual bronchoscopic images and the reproducibility of bronchial folds in CT images. Consequently, MSE was better than NMI in average accuracy of bronchoscope tracking and computation time.
Keywords: endoscope navigation system, mean squared error, normalized mutual information


3次元X線CT像を用いた歯槽骨吸収の深さ測定に関する予備的検討

○長尾滋郎,林雄一郎*,北坂孝幸,森健策,末永康仁,山田章三**,内藤宗孝***
名古屋大学大学院情報科学研究科
*名古屋大学大学院工学研究科
**愛知学院大学歯学部歯周病学講座
***愛知学院大学歯学部歯科放射線学講座

A Preliminary Study of Bone Resorption Extraction and Automated Measurement of Its Depth Using 3-D X-Ray CT Images

○Jiro Nagano,Yuichiro Hayashi*, Takayuki Kitasaka, Kensaku Mori, Yasuhito Suenaga, Shohzoh Yamada**, Munetaka Naitoh***
Graduate School of Information Science , Nagoya University
*Graduate School of Engineering, Nagoya University
**Department of Periodontology, School of Dentistry, Aichi-Gakuin University
***Department of Oral and Maxillofacial Radiology, School of Dentistry, Aichi-Gakuin University

Abstract: This paper describes a preliminary study on estimation of the region of alveolar bone resorption and automated measurement of its depth . Measurement of the depth of bone resorption is an important index of the extent of periodontitis. Although it is physically measured by inserting a probe, the insertion is difficult on the interproximal sides. The resorption is also examined by using dental X-ray images. In this case, the depth is measured as the distance between cement-enamel junction (CEJ) and the bottom of the resorption. The X-ray examination has the advantage of being able to measure the depth even on the inter- proximal sides. However, there is no report on automated resorption depth measurement using dental 3-D X-ray CT images. Our methods use dental CT images to estimate the bone resorption region and automatically measure the resorption depth around the tooth of interest. The experimental results showed that the proposed methods could be used to extract alveolar bone resorption and measure its depth.
Keywords: bone resorption, automated measurement, 3-D dental CT


硬膜外腔への穿刺反力の計測

苗村潔1, 田口良秋1, 齋藤英也2, 鷲尾利克3, 篠原一彦1, 軽部征夫1
1.東京工科大学バイオニクス学部
2.潟ニシス
3.産業技術総合研究所人間福祉医工学研究部門

Measurement of resistance force during epidural puncture

K.Naemura1, Y.Taguchi1, H.Saito2, T.Washio3, K.Shinohara1,I.Karube1
1.School of Bionics, Tokyo University of Technology
2.UNISIS Corp.
3.Institute for Human Science and Biomedical Engineering , National Institute of Advanced Industrial Science and Technology

Abstract: In order to clarify the design strategy of an epidural anesthesia needle, measurement of resistance force during epidural puncture and development of a simulator are essential . At first , authors conducted an animal experiment to measure the resistance force. A male pig (weight 40 kg) was employed .One surgeon as professinal and three amateurs did the epidural anesthesia using a handy-type force sensor attached a clinical needle (17G). Data showed the difference between the professional and amateurs. Force waveform of the professional subject had only one peak, whereas that of the amateur subjects showed several peaks. Times from inserting the needle till getting out were ten seconds for the professional , thirty seconds for the amateurs.
Keywords: Epidural anesthesia, Resistance force, Needle , Puncture


心拍動追従ロボットシステムを目指した,超小型加速度センサを用いたリアルタイム運動計測
−動物実験による心拍データの測定−

Real-Time Movement Measurement using Micro Acceleration Sensor which aimed at Robot System Chasing Heatbeat
Measurement of the heart pulsation data based on an animal experiment

○岡部康弘,佐々木大輔,岡本淳(早大),岡野光男(東京女子医),藤江正克(早大)
Yasuhiro Okabe, Daisuke Sasaki, Jun Okamoto (Waseda University)
Mitsuo Okano(Tokyo Women's Medical College)
Masakatsu Fujie(Waseda Uhiversity)

Abstract: This paper proposes a method for heartbeat measurement using a micro acceleration sensor. It succeeded in taking the acceleration and the force of the heat pulse of an animal . It newly experimented using a sensor with a very sufficient system called an electrostatic capacitance type acceleration sensor, and drawn-in type stabilizer type measurement equipment was developed . We plan to develop the operation robot based on this data.
Keywords: micro acceleration sensor, cardiac surgery, minimally invasive surgery


左室形成術支援のための有限要素解析による心機能評価ツールの開発

○徳安達士a, 一矢明人a, 喜多村直b, 坂口元一c, 米田正始c
a.九州工業大学情報工学研究科
b.九州工業大学情報工学部
c.京都大学心臓血管外科

Development of tool for evaluation of cardiac function by using F.E.M. for a left ventricular plasty surgery

T.Tokuyasu a, A.Ichiya a, T.Kitamura b, G.Sakaguchi c, M.Komeda c
a.Graduate Course of Information Engineering , Kyushu Institute of Technology, Iizuka, Japan
b.Dept. of Medical Systems Engineering Kyushu Institute of Technology, Iizuka, Japan
c.Dept. of Cardiovascular Surgery, Faculty of Medicine Kyoto University, Kyoto, Japan

Abstract: For cardiac plastic surgery, pressure-volume graph (P-V loop) is used to evaluate the heart function of a patient. We have developed the cardiac muscle palpation system, and it have been appreciated from the cardiac surgeons. Recently, volume reduction test using a heart lung machine is applied to the patient heart in the operating room for improving the surgical efficiency, where the cardiac surgeons can estimate the efficient volumic range for pumping ability of heart. To add an evaluation tool of the cardiac function into our system have been required from the cardiac surgeons. In order to build the cardiac functional evaluation tool, F.E.M. analysis is used for a simple heart model during one cardiac cycle . This paper presents how to identify the young modules of the left ventricular muscle changing during a cardiac cycle by using P-V loop by a living dog, and shows the simulation results . As future work , we are going to make the virtual heart model from the patient's heart images and to apply the presente methods on it.
Keywords: F.E.M. analysis, Heart function, Virgual heart, and Volume reduction test.


術中の臓器変形を追跡するための3次元形状測定装置の開発

○片岡弘之1, 大内克洋1, 中村真人1, 坂本徹2, 高谷節雄1
1.東京医科歯科大学生体材料工学研究所
2.東京医科歯科大学医歯学総合研究科

Development of a 3-D Digitizer for Tracking Intraoperative Deformation of Organs

H.Kataoka1, K.Ohuchi1, M.Nakamura1, T.Sakamoto2, S.Takatani1
1.Institute of Biomaterials and Bioengineering , Tokyo Medical and Dental University, Tokyo, Japan
2.Graduate School , Tokyo Medical and Dental University, Tokyo , Japan

Abstract: Adaptation of surgical navaigation to organ deformation is desired for theimprovement of the system in terms of its accuracy and functionality . In this study, as a means to obtain real-time quantitative data of intraoperative organ deformation, we appended mobility to a 3-D digitizer with keeping the 3-D shape representation in the unique coordinate system in an operation room . Optical markers were attached on the 3-D digitizer, and its motion was tracked by a 3-D localizer. The 3-D shape data obtained by the 3-D digitizer was represented in the optical marker coordinate system using a calibrated transformation matrix, and then it was represented in the 3-D localizer coordinate system according to the position tracking of the optical markers. The accuracy of each device was under 0.4 mm in mean value , but the accuracy of the whole system was up to 2.5 mm in mean value. The speed of contimuous data acquisition was 1.8 sec/frame in the low resolution mode, this was considered to be enough for surgical navigation.
Keywords: surgical navigation, organ deformation, 3-D digitizer, 3-D localizer


複数のカメラ視野画像により計測した肝表面形状を基に内部構造の変形を獲得するData Fusionシステムの開発

○植松美幸a, 鈴木直樹b, 服部麻木b, 大竹義人b, 林部充弘b, 鈴木薫之b, 小林進c, 内山明彦a
a. 早稲田大学大学院理工学研究科生命理工学専攻
b. 東京慈恵会医科大学高次元医用画像工学研究所
c. 東京慈恵会医科大学外科学講座

Development of a Data Fusion System to Acquire the Inner Structures Based on Liver Surface Shape captured by Stereo Cameras from Multi-Directions

Miyuki Uematsu a, Naoki Suzuki b, Asaki Hattori b, Yoshito Otake b, Mitsuhiro Hayashibe b, Shigeyuki Suzuki b, Susumu Kobayashi c, Akihiko Uchiyama a
a.Graduate School of Science and Engineering ,Waseda University, Tokyo, Japan
b.Institute for High Dimentional Medical Imaging, Jikei Univeristy School of Medicine, Tokyo, Japan
c.Department of Surgery, Jikei University School of Medicine, Tokyo, Japan

Abstract: In order to perform the operations safely, it is essential to have a clear grasp of the three-dimensional (3D) relationship between the target and inner structures. However, abdominal organs such as the liver deform considerably during the operation. It is difficult for surgeons to imagine the inner structures of the organs spatially with preoperative data. Our aim is to develop a data fusion system for liver surgery which assists surgeons to intuitively visualize the inner structures of organs. To realize the system , we use preoperative image data and intraoperative surface movement data captured by cameras from multiple directions. A 3D model was reconstructed with preoperative data to preserve the structual organ information. As well , surface movement data was acquired by using color information from cameras and the preoperative model was mapped onto the intraoperative surface data. Intraoperative inner structures of the organs were provied to modify the preoperative 3D model with the surface movement data. In this paper , we present and evaluate the feasibility of measurement with a stereo camera in the intraoperative environment through an animal experiment.
Keywords: data fusion, open surgery, deformable model , stereopsis


Volume Data を対象としたリアルタイム変形処理法[第2報)−弾性モデルにおける自由な切開面の生成−

○瀧本祟博a, 鈴木直樹b, 服部麻木b, 鈴木薫之b, 林部充弘b, 大竹義人b, 小林進c , 内山明彦a
a.早稲田大学理工学部
b.東京慈恵会医科大学高次元医用画像工学研究所
c.東京慈恵会医科大学外科学講座

Real-Time Volume Data Deformation for Surgical Simulation 2nd Report- Making of Various Incision planes for Elastic Model-

○Takahiro Takimoto a, Naoki Suzuki b, Asaki Hattori b, Shigeyuki Suzuki b, Mitsuhiro Hayashibe b, Yoshito Otake b, Susumu Koyabayshi c, Akihiko Uchiyama a
a. Department of Science and Engineering , Waseda University
b. Institute of High Dimentional Medical Imaging, jikei University School of Medicine
c.Department of Surgery, Jikei University School of Medicine

Abstract: We have been developing a virtual surgery system that can simulate surgical maneuvers on elastic organs with haptic feedback. In order to simulate such surgical technique in real time, we have constructed an elastic organ model called a sphere-filled model that is suited for real time and quantitative deformation. In this research, our purpose is to make various incision planes according to surgical techniques in real time by using volume data. In order to deform the volumetric model , we adopted the rhombic dodecahedron as the formation of the voxel group assigned to the sphere and the formation that follows the motion of each sphere. Moreover, we could monitor the deformation of the surface and the inner structures by superimposing the surface model onto the volumetric model. By using this method and modifying this model, we could make a deeper incision in the same region and a slanting incision that approached the resection for volume data without losing current imaging speed . Consequently , we were able to perform not only pushing and pinching but various incisions that approached the resection in this system.
Keywords: virtual surgery system, volume data, incision


In-vivo 計測により得られた反力応答データベースを用いた軟組織モデルを有する手術シュミレーションシステム

○鈴木薫之a, 鈴木直樹a, 服部麻木a, 林部充弘a, 大竹義人a, 瀧本祟博b, 内山明彦b, 小林進c
a.東京慈恵会医科大学高次元医用画像工学研究所
b.早稲田大学理工学部
c.東京慈恵会医科大学外科学講座

Soft Tissue Model with the Haptic Response's Database for Surgical Simulation System

Shigeyuki Suzuki a, Naoki Suzuki a, Asaki Hattori a, Mitsuhiro Hayashibe a, Yoshito Otake a, Takahiro Takimoto b, Akihiko Uchiyama b, Susumu Kobayashi c
a.Institute for High Dimensional Medical Imaging , The Jikei University School of Medicine, Tokyo, Japan
b.School of Science and Engineering , Waseda University, Tokyo, Japan
c.Department of Surgery, The Jikei University School of Medicine, Tokyo, Japan

Abstract: We have been developing a virtual surgery system which uses a sphere-filled model on elastic organs, Furthermore, we have conncted a dual force feedback device to this organ model to provide the user with force feedback , specifically the sensations of touch and force. In such a surgical simulator, it is important for the system to apply the realistic organ deformation and realistic haptic feedback . In this study, to apply the quantitative haptic feedback to the system , we measured the relationship between the surface deformation value of the soft tissue and the pressure that is shown by the compress device in in-vivo experiments. Also, we made a database based on the measurements, and adapted the database for our surgical simulation system. As a result, this system allows the user to simulate the surgical maneuvers with a soft tissue model which not only performs the real time deformation but also has the property of quantitative haptic response.
Keywords: sorf-tissue model, haptic response, surgical simulation, in-vivo experiment


画像誘導手術のための高画質三次元画像提示システムの構築

廖 洪恩1, 岩原 誠1, 波多伸彦1,佐久間一郎2, 土肥健純1
1.東京大学大学院情報理工学系研究科
2.東京大学大学院新領域創成科学研究科

An Autostereoscopic Display System for Image- guided Surgery using High-quality 3-D Image

Hongen Liao1, Makoto Iwahara1, Nobuhiko Hata1, Ichiro Sakuma2, Takeyosi Dohi1
1. Graduate School of Information Technology Science, The University of Tokyo
2. Graduate School of Frontier Sciences , The University of Tokyo

Abstract: This paper presents a high- quality glass -less autostereoscopic display system that is itegrantd into image-guided surgery. The glass-less autostereoscopic image was created by employing a modification of Integral Videography (IV) , which is an animated extension of Integral Photography. IV records and reproduces 3-D images using a micro convex lens array and plat display , which can display geometrically accurate 3-D autostereoscopic images and reproduce motion parallax without any need for special viewing devices. This paper reports the use of high -resolution IV display and high performance computing for producing medical 3-D image. We evaluate the feasibility of this display by using a set of medical image with segmentation and reproducing 3-D CT and MRI autostereoscopic image for surgical planning and intra-operative guidance. The main contribution of this paper is application and modification of medical 3-D display technique originally developed in high-resolution autostereoscopic display and high performance computing.
Keywords: integral videography, integral photography, autosteroscopic, 3-D image processing


Integral Videography (IV) の診断時利用システムの実用化

○酒井伸幸a, 波多伸彦a, 廖 洪恩a, 中島勧b, 高本眞一c, 土肥健純a
a.東京大学大学院情報理工学系研究科
b.東京大学医学部整形外科
c.東京大学医学部心臓外科

The system of Diagnostic Display With Integral Videography

Nobuhiko Sakai a, Nobuhiko Hata a, hongen Liao a, Susumu Nakajima b, Shinichi Takamoto c, Takeyoshi Dohi a
a.Graduate School of Information Science and Technology , University of Tokyo
b.Department of Orthopedic Surgery, Graduate School of Medicine, Univ. of Tokyo
c.Department of Cardiothoracic Surgery, Univ. of Tokyo

Abstract: The stereoscopic pictures obtained from Magnetic Resonance Image(MRI) etc. are used for an diagnostic and operation-supporting picture. One of the stereoscoic methods is integral videography (IV) , we have developed based on integral photography, projecting a computer-generated graphical object. Furthermore using parallel processing method integrating Message Passing Inteerface (MRI)on High Performance Computer (HPC), we shortened the calculating time of IV picture by the shortest at about 0.1 seconds. Now, by using socket communication it transmitted to another portable note PC, which is for a display, and we used 3D -Slicer for the controller of IV image and displaying tomograms. Then, we achieved the fast presentation of tomograms and stereoscopic pictures seen from arbitrary direction that was specified with the 3D - Slicer at anywhere we can access to the network.
Keywords: MPI, Integral Photography, Integral Videography, parallel Rendering, 3D-Slicer


Open MRI 誘導手術における脳腫瘍術中セグメンテーション

○猪股崇*, 村垣善浩**,伊関洋**,土肥健純**,波多伸彦*
*東京大学大学院情報理工学系研究科
**東京女子医科大学脳神経センター

Intraoperative Segmentation of Brain Tumors for Open MRI Guided Surgery

Takashi Inomata*, Yoshihiro Muragaki**, Hiroshi Iseki**, Takeyoshi Dohi**, Nobuhiko Hata*
*Graduate School of Information Science and Technology, The University of Tokyo
**Department of Neurosurgery, Neurological Institute, Tokyo Women's Medical University

Abstract: This paper presents an intraoperative segmentation of brain tumors for open MRI guided surgery. The intraoperative segmentation can show the tumor margin and the representative measurement of tumor size during the surgery. Fuzzy Connectedness (FC) method was used , which has a strong robustness to image noises. The method was validated in five patients aged 32-66 years with gliomas. FC segmentation was performed on axial T2-weighted image, where brain tumors have high intensity. Each MR data was segmented manually by a neurosurgeon and was employed as true segmentation. Then Correspondence Ratio (CR) and Percent Match (PM) , which are equal to 1 when perfectly matched , were caluculated between manual and automatic segmentation results. The accuracy results showed that average CR and PM were 0.75 and 0.81 respectively, which are sufficient considering the signal -to-noise ratio and voxel resolution of Open MRI. The validation in the tumor resection rate was also performed and the results showed the presented segmentation can estimate the tumor resection rate precisely in 92% . It cah be concluded that the presented segmentation can precisely track the size of brain tumor as it responds to treatment during Open MRI guided surgery.
Keywords: Brain tumor, sdgmentation, intraoperative


四次元筋肉モデルを用いた人工股関節患者の股関節駆動シュミレーションシステム

○大竹義人a, 三木秀宣b, 山村在慶c, 中村宣雄c, 鈴木直樹a, 服部麻木a, 菅野伸彦b, 米延策雄d, 越智隆弘e
a.東京慈恵会医科大学高次元医用画像工学研究所
b.大阪大学大学院医学系研究科
c.協和会病院
d.国立大阪南病院整形外科
e.大阪大学大学院医学系研究科医工学治療学

Hip Joint Motion Simulation System by Using the 4-dimensional Muscle of the Patient after Total Hip Arthroplasty

○Yoshito Otake a, Hidenobu Miki b, Mitsuyoshi Yamamura c, Nobuo Nakamura c, Naoki Suzuki a, Asaki Hattori a, Nobuhiko Sugano b, Kazuo Yonenobu d, Takahiro Ochi e
a.Institute for High Dimensional Medical Imaging , Jikei Univ. Sch. of Med
b.Department of Orthopaedics, Osaka University Graduate Sch. of Med.
c.Kyowa-kai Hospital
d.Department of Orthopaedic Surgery, Osaka Minami National Hospital
e.Department of Computer Integrated Orthopaedics, Osaka University Graduate Sch. of Med.

Abstract: We have been developing a 4-dimensional motion analysis system for patients having had total hip arthroplasty (THA) . This system aims to simulate the patient's skeletal movement and estimates the complications after THA. However, the causes of the complications such as dislocation are influenced not only by the movement of the skelton but also by the muscle force induced by the surrounding muscles. Therefore, we added the 4-dimensional muscle model to the skeltal model. In order to estimate the direction of the muscle force and the length of the muscles , we have developed a string - typed muscle model which represents the route of the muscles. The strings expand and contact according to the movement of an origin and an insertion of the muscle . We developed models of the five muscles related to the movement of the hip joint . To estimate the precise route of the muscles during hip motion, we calculated the interference between bones and muscles , so that the muscle moves on the bone surface . By using this model , clinicans can predict the potential for dislocation or recognize the causes of dislocation, including the influence of the muscles .
Keywords: 4D muscle model, total hip arthorplasty (THA) , dislocation


4次元下顎運動測定システムの精度についての検証

○小川匠,重田優子,須摩真由美,安藤栄里子,福島俊士,小林馨*,大竹義人**,服部麻木**,鈴木直樹**
鶴見大学歯学部歯科補綴学第2講座
*鶴見大学歯学部歯科放射線学教室
**東京慈恵会医科大学総合医科学研究センター高次元医用画像工学研究所

Verification of precison about 4-dimensional analysis of mandibular movement

Takumi Ogawa, Yuko Sigeta, Mayumi Suma, Eriko Ando, Shunji Fukusima, Kaoru Kobayashi*, Yoshito Otake**,Asaki Hattori**, Naoki Suzuki**
The 2nd Department of Prosthetic Dentistry Tsurumi University School of Dental Medicine
*Department of Oral Radiology Tsurumi University School of Dental Medicine
**Institute for High Dimensional Medical Imaging, Jikei University School of Medicine

Abstract: In the medical field, the 4-dimensional human body model combined reconstructed 3-dimensional image data (CT and MRI)and exercise data of human body was gradually applied in some clinical cases. We applied this technique to the mandibular movement analysis in the dentistry domain, and develop the 4-dimensional analyzing system for mandibular movement.The aim of this sutdy was to inspect the precision of this analyzing system. A dry skull was used in this study, and the mandible was fixed by each mandibular position to the skill . The skull-mandibule relationship of each position was measured by two procedure. At first, a CT measurement was performed and the 3-dimensional image was reconstructed and the true values were established. Secondly, the optical measurement equipment marker with the dental arch was made into positional measurement values. Then, the measurement values were contrasted with the corresponding true values to inspect measurement errors between them.As a result, it became clear that the RMS errors of the 4-dimensional analyzing system of mandibular movement was at an average of ±0.405mm and ±0.431 degree. This shows that this analyzing system has sufficient measurement accuracy for functional examination of temporomandibular disorders.
Keywords: 4-dimensional analysis of mandibular movement , precison, 3 dimensions of reconstitution images


四次元筋肉モデルを用いたスクエアマンディブル患者の咀嚼筋動態の解析

○重田優子a, 小川匠a, 福島俊士a, 鈴木直樹b,大竹義人b, 服部麻木b
a.鶴見大学歯学部歯科補綴学第2講座
b.東京慈恵会医科大学総合医科学研究センター高次元医用画像工学研究所

Analysis of masticatory muscle condition using the 4-dimensional muscle model for a patient with square mandible

Yuko Shigeta a, Takumi Ogawa a, Shunji Fukusima a, Naoki Suzuki b, Yoshito Otake b, Asaki Hattori b
a.The 2nd Department of Prosthetic Dentistry, Tsurumi University School of Dental Medicine
b.Institute for High Dimensional Imaging, Jikei University School of Medicine

Abstract: Purpose: The aim of this study was to analyze the mandibular movement of a patient with square mandible using the 4-dimensional (4D) analyzing system, and to suppose the cause of square mandible from charasteristics of the movements. Method: Subjects were a healty volunteer and a patient with square mandible. A volunteer was a 26-year old female who had no missing teeth and no morbid findings in clinical examination. A patient was a 37-year old female.Diagnostic imaging scarcely depicted any disc derangement, but a severely limited jaw opening was noted . As well , her facial appearance showed a characteristic square mandible facial configuration. The skull and mandible were reconstructed into a 3-dimensional (3D) bone model from the CT data and mandibular movements were recorded by a measurement device of MM-JI-E (Shofu Inc.). The bone model and the mandibular movements were combined using the 4D analyzing system. The origin and halt of each masticatory muscle were positioned on the surface of the 3D bone model , and connected together with a string respectively. In this system , the color of the string was designed to be passively canged in accordance with mandibular movements. Results and Discussion: In this case, the cause of opening linitation was not the opening muscle itself but contraction of the temporal muscle. Therefore, it was supposed that the load extended to the masseter muscle from the temporal muscle depended on the masseter muscle, and resulted in muscle hypertrophy or angle hyperplasia.
Keywords: Four-dimensional analysis, Mandibular movement, Masticatory muscle model, Sqare Mandible.